|
Symbol Name ID |
Mybpc3
myosin binding protein C, cardiac MGI:102844 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Right atrial enlargement |
Muscular ventricular septal defect |
Ventricular septal hypertrophy |
Ventricular hypertrophy |
Left ventricular noncompaction |
Dilated cardiomyopathy |
Hypertrophic cardiomyopathy |
Myofiber disarray |
Pericardial effusion |
Cardiomegaly |
Stroke |
Transient ischemic attack |
Reduced left ventricular ejection fraction |
Increased left ventricular end-diastolic volume |
Pulmonary arterial hypertension |
Cardiac arrest |
Sudden cardiac death |
Ventricular fibrillation |
Atrioventricular block |
First degree atrioventricular block |
Left bundle branch block |
Right bundle branch block |
Congestive heart failure |
Syncope |
| Disease(s) Associated with MYBPC3 | ||||||||||||||||||||||||
| dilated cardiomyopathy 1MM | ||||||||||||||||||||||||
| hypertrophic cardiomyopathy 4 |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal myocardial fiber morphology |
abnormal myocardial fiber mitochondrial morphology |
increased myocardial fiber size |
myocardial fiber degeneration |
myocardial fiber disarray |
abnormal ventricle papillary muscle morphology |
disorganized myocardium |
heart left ventricle hypertrophy |
abnormal heart morphology |
dilated heart left atrium |
increased heart weight |
enlarged heart |
cardiac hypertrophy |
abnormal heart left ventricle morphology |
dilated heart left ventricle |
thick ventricular wall |
cardiac fibrosis |
cardiac interstitial fibrosis |
dilated cardiomyopathy |
dystrophic cardiac calcinosis |
decreased cardiac stroke volume |
abnormal cardiac muscle contractility |
decreased cardiac muscle contractility |
decreased ventricle muscle contractility |
increased cardiac muscle contractility |
abnormal cardiac muscle relaxation |
abnormal heart echocardiography feature |
decreased heart rate |
sinus bradycardia |
abnormal myocardial fiber physiology |
increased response of heart to induced stress |
cardiomyopathy |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||
| Mybpc3tm1.1Jse/Mybpc3tm1.1Jse | ||||||||||||||||||||||||||||||||||
| Mybpc3tm1a(EUCOMM)Hmgu/Mybpc3tm1a(EUCOMM)Hmgu | ||||||||||||||||||||||||||||||||||
| Mybpc3tm1Jse/Mybpc3tm1Jse | ||||||||||||||||||||||||||||||||||
| Mybpc3tm1Lcrr/Mybpc3tm1Lcrr | ||||||||||||||||||||||||||||||||||
| Mybpc3tm1Rmos/Mybpc3tm1Rmos | ||||||||||||||||||||||||||||||||||
| Mybpc3tm2.1Lcrr/Mybpc3tm2.1Lcrr | ||||||||||||||||||||||||||||||||||
| Mybpc3tm1Lcrr/Mybpc3+ | ||||||||||||||||||||||||||||||||||
| Mybpc3tm2.1Lcrr/Mybpc3+ | ||||||||||||||||||||||||||||||||||
| Tg(Myh6-Mybpc3*)24Rbns/0 | ||||||||||||||||||||||||||||||||||
| Tg(Myh6-Mybpc3*)32Rbns/0 | ||||||||||||||||||||||||||||||||||
| Mybpc3tm2.1Rmos/Mybpc3tm2.1Rmos A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ (conditional) |
* | |||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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